Our lab investigates the neural mechanisms underlying the subjective experience of pain. While specialized peripheral nerve cells are typically responsible for initiating pain, there are situations where pain can occur without nociceptor activation. This is because the subjective experience of pain depends on complex patterns of neural activity distributed over several brain regions. Indeed, pain is defined as a conscious experience, and therefore feeling pain requires assessing the short- and long-term meaning of painful sensations for one’s self. Our research aims to uncover how the brain produces pain and to find ways to alleviate it. To achieve this goal, we employ various brain imaging techniques such as MRI, EEG, and MEG, along with psychological and psychophysiological methods like pain ratings, response times, decision-making, nociceptive flexion reflexes, skin conductance responses, and more.